Modular Cleanroom Design

A wide selection of solutions for ISO 1 to ISO 9 Modular Cleanroom Systems

  • At Nicos, we specialize in high-performance cleanroom design, combining advanced engineering, regulatory compliance, and modular innovation. Our cleanroom solutions are built for industries requiring strict contamination control, efficiency, and scalability.
  • Nicos Group offers three levels of service tailored to your project needs:
    1) Design Assist
    2) Architectural Turnkey Design
    3) Turnkey Design inclusive of MEP
  • Our BIM and Revit design services allow for detailed 3D modeling of cleanroom components, enhancing coordination between teams, improving accuracy, and reducing costs and project timelines, ideal for large-scale cleanroom projects.
  • Unlike most of competitors, we manufacture our own cleanroom components, ensuring streamlined communication, faster production, and customized solutions, all while maintaining strict quality control.
  • Our pre-fabricated modular cleanrooms offer quick installation, reduced labor costs, and seamless reconfiguration. With pre-cut MEP openings and scalable designs, our cleanrooms adapt to future expansions and production needs.
  • Discover how Nicos Cleanroom Design can deliver a high-performance, compliant, and cost-effective solution for your industry.

MODULAR CLEANROOMS, BY MODULAR EXPERTS

With over 30 years of experience, Nicos Group Inc. has been a trusted leader in the modular cleanroom industry. Specializing in the design, supply, and installation of Nicomac-Mangini modular cleanrooms, we offer solutions for both non-certified and certified (ISO & GMP) manufacturing and assembly areas. We understand that cleanrooms are more than just functional spaces—they are vital environments that require precision and care. That’s why we focus on special touches and finishes to create a space that is not only highly functional but also a special place for your operations. From the initial design to final installation, our comprehensive project management ensures seamless construction, all handled out of our New Jersey facility.

COMPLIANCE TO ISO, GMP

Nicos Cleanrooms are designed to meet both ISO standards and GMP requirements. While ISO standards focus on maintaining proper air quality and effective contamination control, GMP compliance emphasizes product safety, sterility, and regulatory approval, especially for pharmaceutical and biotechnology applications. Cleanrooms are classified into nine ISO classes, ranging from ISO 1 (the highest level of purity) to ISO 9 (the least stringent), based on permissible particle counts per cubic meter. Nicos offers cleanroom solutions across all these ISO classes to meet the diverse needs of various industries.

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SHOP DRAWINGS AND DESIGN ASSIST

Nicos offers turnkey solutions including cleanroom design assist. With more than 25 years of experience in the industry, our team can provide valuable support to the architects and engineers involved in your project or even design the cleanroom from scratch. Our extensive experience enables us to anticipate design challenges early on, preventing costly issues from emerging during construction.

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BIM AND REVIT EXPERTISE

Nicos customers also have the option to purchase our Revit design and assistance package. Using Building Information Modeling (BIM) with Revit, you can create highly detailed 3D models of cleanroom components, such as walls, ceilings, HVAC systems, filtration, and equipment layouts. This approach enhances coordination between architects, engineers, and manufacturers, while improving cost and time efficiency, accuracy, and future scalability. These benefits are particularly valuable for large projects where precision and integration are critical.

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MEP CLASH DETECTION

MEP (Mechanical, Electrical, and Plumbing) clash detection is a critical process in cleanroom design and construction. It ensures that all systems integrate seamlessly without interfering with the cleanroom’s stringent environmental controls. By employing MEP clash detection early in the design phase, cleanroom projects achieve a reduced risk of errors and avoid expensive design changes in late stages of the project. Detecting issues early significantly reduces expenses, as on-site design changes are typically undesirable and expensive.

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IN-HOUSE DESIGN, IN-HOUSE PRODUCTION

At Nicos, we manufacture our own products: this is one of the most important point of difference between Nicos and its competitors. Integrating both design and production processes in-house offers significant benefits for cleanroom projects: it enhances project control, streamlines communication, enables tailored solutions and flexibility, and reduces project timelines.

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CUSTOMIZED PRE-FABRICATION

Nicos combines the advantages of prefabrication with the freedom of tailor-made design to deliver cleanroom solutions that are both efficient and highly customizable. Our prefabrication process maximizes factory production, allowing for faster on-site assembly of pre-manufactured elements, significantly reducing project timelines. With in-house production ensuring industrial precision and consistent quality, we minimize errors and eliminate unforeseen challenges during installation. Beyond speed and precision, Nicos offers unparalleled flexibility to create custom solutions tailored to your unique needs, including a wide range of finish options seamlessly embedded into our industrial processes.

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FLEXIBILITY DAY 2

Nicos cleanroom systems are designed with adaptability in mind, offering unparalleled flexibility to modify layouts even after installation. Our unique tailored profiles feature customizable leave-outs, allowing easy maintenance or the insertion of new, large equipment into the cleanroom space. For specific openings, we’ve developed an innovative double aluminum extrusion profile to ensure seamless integration when changes are required. At the end of the cleanroom’s lifecycle, our systems are designed for disassembly, reuse, and 100% recycling of materials like steel, ensuring they retain value and avoid waste. With precision prefabrication, we produce only what is needed, delivering sustainable, efficient, and future-ready cleanroom solutions.

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ANY PROJECT SIZE, ANY APPLICATION

At Nicos-Mangini, we work on projects of all sizes, no matter the industry. From small compounding pharmacies with 1-2 rooms to mid-sized pharmaceutical and life science facilities, all the way up to full modular hospitals and gigafactories over 100,000 square feet for semiconductors or EV batteries—we’ve got the experience and team to handle it.

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CASE STUDIES

DNA LAB Renovation and retrofit in historical building at yale campus

CLEANROOM FOR COMPOUNDING PHARMACY AT THE UNiveristy of nevada

SPECIAL vivarium design for walkable ceiling at animal research facility

gigafactory at ford's battery center of excellence in romulus

vaccine facility for gates foundation funded initiative in washington state

transition from a research to manufacturing facility in kalexsyn, MI

CASE STUDIES

3 OFF-SITE CONSTRUCTION SOLUTIONS

Prefabricated Modular

  • Permanent prefabricated solution
  • Perfect alternative to traditional construction systems
  • Ideal for emergency situations as it allows existing environments to be equipped or converted quickly and flexibly
  • Compatible with the use of high-performance materials
  • Greater flexibility in the organization of internal spaces compared to the container solution
  • Ideal for "courtyard" type campus extensions

Modular Container

  • Option of rapid dismantling and reinstallation at other sites and in emergency situations
  • Intended uses: hospitals, civil protection emergencies, construction sites, schools, barracks, etc.
  • Easy transport and handling, durability, no need for maintenance
  • "Plug and play" system
  • Option of supply fully equipped with systems and equipment
  • Typical "POD" / Podular application

My Cubik

  • Patented hybrid system by Mangini
  • Permanent prefabricated solution, versatile and multifunctional
  • Integrated and complete structure of embedded systems
  • Extreme speed of installation and remodeling
  • Ease of transport is key
  • Available both as "My Cubik Lite" and "My Cubik Embedded"

Process and architectural design GMP lay out consulting
Nicos group with you from design to completion.

Services provided out of our North American facilities:

  • Full turn key project management
  • Turn key clean room installation services
  • From Basic Design to construction
  • After sales service and troubleshooting
  • Design qualification through internal drafting department
  • Shipping, Logistics, warehousing services
  • Installation project management
  • Supervision and coordination of third party trades (flooring, ducting, electrical, fire suppressions)
  • Installation and start up of access control systems
  • Approvals, certification, validation support
  • BIM design
  • Spare parts